Zhan/Jin Laboratory
Advancing cancer neuroscience and immunotherapy for brain tumors through innovative CAR-T cell engineering and translational research
Our Mission
Glioblastoma (GBM) remains one of the most devastating brain tumors, with limited treatment options and poor survival rates. Our laboratory focuses on understanding the complex interactions between the immune system and brain tumors, developing novel immunotherapeutic approaches, particularly CAR-T cell therapies, to overcome the immunosuppressive tumor microenvironment and improve patient outcomes.
We integrate cutting-edge cancer neuroscience, cancer immunology, and cellular engineering to tackle fundamental questions about how brain tumors evade immune surveillance and how we can harness the immune system to fight back.
Research Focus
Cancer Neuroscience
Investigating the unique neurobiological features of brain tumors and their microenvironment to identify novel therapeutic targets.
Cancer Immunology
Understanding immune dysfunction in glioblastoma and developing strategies to enhance anti-tumor immunity.
CAR-T Cell Therapy
Engineering chimeric antigen receptor T cells with enhanced tumor-targeting, persistence, and efficacy against solid tumors.
Glioblastoma Research
Characterizing mechanisms of treatment resistance and developing combination therapeutic strategies for GBM.
Neuro-oncology
Translating laboratory discoveries into clinical applications to improve outcomes for patients with brain tumors.
Latest News
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Welcome to the Zhan/Jin Laboratory Website
December 06, 2025We are excited to launch the new Zhan/Jin Laboratory website! This platform will serve as a hub for sharing our research, connecting with collaborators, and communicating with prospective students and postdoctoral fellows.
Join Our Team
We welcome motivated students, postdoctoral fellows, and visiting scholars with backgrounds in immunology, neuroscience, molecular biology, bioengineering, or related fields. If you are passionate about advancing cancer immunotherapy and making a difference in patients' lives, please reach out to us.